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DSIP (Delta Sleep-Inducing Peptide) is a synthetic nonapeptide, a nine-amino-acid neuropeptide first isolated from the cerebral venous blood of animals. It belongs to the regulatory neuropeptide class.
In the published preclinical literature, DSIP has been characterised at the neurochemical-model level for its association with slow-wave (delta) cortical electroencephalogram signalling, for transport across the blood-brain barrier, and for time-of-day dependent modulation of a pineal enzyme in cultured and animal models. It is supplied as a research compound and is not intended for human or veterinary use.
DSIP has been characterised in preclinical laboratory models. The primary studies below, in animal and in-vitro neural models, recorded electrophysiological, transport, and enzyme-activity endpoints, with the work centred on the nonapeptide’s slow-wave cortical signature and its handling by the central nervous system. The literature is preclinical; it describes the compound, not any outcome in humans.
Animal model
Characterisation of a delta-electroencephalogram-inducing nonapeptide in the rabbit
Schoenenberger & Monnier · 1977 · Proceedings of the National Academy of Sciences USA
In a rabbit model under double-blind conditions, the synthesised nonapeptide was infused intraventricularly and the cortical electroencephalogram was recorded; the synthetic peptide reproduced the slow-wave (delta) spectral signature measured for the natural isolate.
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Animal model
Transport of the synthetic peptide DSIP across the blood-brain barrier in the rabbit
Monnier et al. · 1977 · Experientia
In a rabbit model, intravenously administered synthetic DSIP was tracked into the central nervous system and the cortical delta electroencephalogram band was measured, an endpoint used to index transit of the peripherally given peptide across the blood-brain barrier.
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Full documentation, on the record. A Certificate of Analysis and a Safety Data Sheet are available on request for every batch.
Links open the original study on PubMed. For research and educational purposes, descriptive of the published preclinical literature, not therapeutic claims about any ai-peptides product.